Catecholaminergic and cholinergic systems of mouse brain are modulated by LMN diet, rich in theobromine, polyphenols and polyunsaturated fatty acids.

Fernández-Fernández, Laura; Esteban, Gerard; Giralt, Mercedes; Valente, Tony; Bolea, Irene; Solé, Montse; Sun, Ping; Benítez, Susana; Morelló, José Ramón; Reguant, Jordi; Ramírez, Bartolomé; Hidalgo, Juan; Unzeta, Mercedes

Fernández-Fernández, Laura; Esteban, Gerard; Giralt, Mercedes; Valente, Tony; Bolea, Irene; Solé, Montse; Sun, Ping; Benítez, Susana; Morelló, José Ramón; Reguant, Jordi; Ramírez, Bartolomé; Hidalgo, Juan; Unzeta, Mercedes.

Affiliation

Fernández-Fernández L; Institute of Neurosciences, and Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain. Mercedes.unzeta@uab.es.

Food Funct ; 6(4): 1251-60, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25756794

Subject(s)

Aging/drug effects; Cholinergic Neurons/drug effects; Fatty Acids, Unsaturated/administration & dosage; Hippocampus/drug effects; Polyphenols/administration & dosage; Theobromine/administration & dosage; Acetylcholinesterase/metabolism; Alzheimer Disease/prevention & control; Animals; Cacao/chemistry; Catechol O-Methyltransferase/genetics; Catechol O-Methyltransferase/metabolism; Cell Differentiation/drug effects; Cell Line, Tumor; Choline O-Acetyltransferase/metabolism; Cholinergic Neurons/metabolism; Chromatography, High Pressure Liquid; Cognition/drug effects; Diet; Dopamine/metabolism; Gene Expression Regulation; Glutathione Peroxidase/genetics; Glutathione Peroxidase/metabolism; Hippocampus/cytology; Hippocampus/metabolism; Humans; Male; Mice; Mice, 129 Strain; Norepinephrine/metabolism; PC12 Cells; Rats; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Theobromine / Aging / Fatty Acids, Unsaturated / Cholinergic Neurons / Polyphenols / Hippocampus Limits: Animals / Humans / Male Language: En Journal: Food Funct Year: 2015 Document type: Article Affiliation country: Spain Country of publication: United kingdom

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