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Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy.
Leverson, Joel D; Phillips, Darren C; Mitten, Michael J; Boghaert, Erwin R; Diaz, Dolores; Tahir, Stephen K; Belmont, Lisa D; Nimmer, Paul; Xiao, Yu; Ma, Xiaoju Max; Lowes, Kym N; Kovar, Peter; Chen, Jun; Jin, Sha; Smith, Morey; Xue, John; Zhang, Haichao; Oleksijew, Anatol; Magoc, Terrance J; Vaidya, Kedar S; Albert, Daniel H; Tarrant, Jacqueline M; La, Nghi; Wang, Le; Tao, Zhi-Fu; Wendt, Michael D; Sampath, Deepak; Rosenberg, Saul H; Tse, Chris; Huang, David C S; Fairbrother, Wayne J; Elmore, Steven W; Souers, Andrew J.
Affiliation
  • Leverson JD; AbbVie Inc., North Chicago, IL 60064, USA. joel.leverson@abbvie.com.
  • Phillips DC; AbbVie Inc., North Chicago, IL 60064, USA.
  • Mitten MJ; AbbVie Inc., North Chicago, IL 60064, USA.
  • Boghaert ER; AbbVie Inc., North Chicago, IL 60064, USA.
  • Diaz D; Genentech Inc., South San Francisco, CA 94080, USA.
  • Tahir SK; AbbVie Inc., North Chicago, IL 60064, USA.
  • Belmont LD; Genentech Inc., South San Francisco, CA 94080, USA.
  • Nimmer P; AbbVie Inc., North Chicago, IL 60064, USA.
  • Xiao Y; AbbVie Inc., North Chicago, IL 60064, USA.
  • Ma XM; Genentech Inc., South San Francisco, CA 94080, USA.
  • Lowes KN; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.
  • Kovar P; AbbVie Inc., North Chicago, IL 60064, USA.
  • Chen J; AbbVie Inc., North Chicago, IL 60064, USA.
  • Jin S; AbbVie Inc., North Chicago, IL 60064, USA.
  • Smith M; AbbVie Inc., North Chicago, IL 60064, USA.
  • Xue J; AbbVie Inc., North Chicago, IL 60064, USA.
  • Zhang H; AbbVie Inc., North Chicago, IL 60064, USA.
  • Oleksijew A; AbbVie Inc., North Chicago, IL 60064, USA.
  • Magoc TJ; AbbVie Inc., North Chicago, IL 60064, USA.
  • Vaidya KS; AbbVie Inc., North Chicago, IL 60064, USA.
  • Albert DH; AbbVie Inc., North Chicago, IL 60064, USA.
  • Tarrant JM; Genentech Inc., South San Francisco, CA 94080, USA.
  • La N; Genentech Inc., South San Francisco, CA 94080, USA.
  • Wang L; AbbVie Inc., North Chicago, IL 60064, USA.
  • Tao ZF; AbbVie Inc., North Chicago, IL 60064, USA.
  • Wendt MD; AbbVie Inc., North Chicago, IL 60064, USA.
  • Sampath D; Genentech Inc., South San Francisco, CA 94080, USA.
  • Rosenberg SH; AbbVie Inc., North Chicago, IL 60064, USA.
  • Tse C; AbbVie Inc., North Chicago, IL 60064, USA.
  • Huang DC; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.
  • Fairbrother WJ; Genentech Inc., South San Francisco, CA 94080, USA.
  • Elmore SW; AbbVie Inc., North Chicago, IL 60064, USA.
  • Souers AJ; AbbVie Inc., North Chicago, IL 60064, USA.
Sci Transl Med ; 7(279): 279ra40, 2015 Mar 18.
Article in En | MEDLINE | ID: mdl-25787766
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Proto-Oncogene Proteins c-bcl-2 / Neoplasms Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Proto-Oncogene Proteins c-bcl-2 / Neoplasms Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States