New systemic agents in dermatology with respect to fertility, pregnancy, and lactation.
J Dtsch Dermatol Ges
; 13(4): 277-89; quiz 290, 2015 Apr.
Article
in En
| MEDLINE
| ID: mdl-25819232
ABSTRACT
With the increasing use of new, predominantly biologic drugs in dermatology, questions frequently arise in clinical practice as to their safety in women wishing to conceive as well as during pregnancy and lactation. Apart from the Summary of Product Characteristics and the Physician's Desk Reference, reliable information may be obtained from databases such as the one compiled by the Center for Pharmacovigilance and Consultation on Embryonal Toxicology at Charité University Medical Center Berlin (https//www.embryotox.de). Another source of information is researching recent publications, for example via PubMed (http//www.ncbi.nlm.nih.gov/pubmed). This article presents current knowledge from the sources mentioned above, and gives detailed information about the use of new biologic agents in women wishing to conceive as well as during pregnancy and lactation. Drugs reviewed include infliximab, adalimumab, etanercept, metastatic for psoriasis, vemurafenib, dabrafenib, imatinib, ipilimumab for melanoma, vismodegib for basal cell carcinoma, rituximab for cutaneous lymphoma as well as omalizumab and anakinra used in the treatment of allergies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications
/
Skin Diseases
/
Biological Products
/
Lactation
/
Dermatologic Agents
/
Fertility
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J Dtsch Dermatol Ges
Journal subject:
DERMATOLOGIA
Year:
2015
Document type:
Article
Publication country:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY