[Progress on establishment of animal model of osteoarthritis by intra-articular injection].
Zhongguo Gu Shang
; 28(1): 90-5, 2015 Jan.
Article
in Zh
| MEDLINE
| ID: mdl-25823143
ABSTRACT
Osteoarthritis (Osteoarthritis, OA) is a common clinical degenerative joint disease with increased incidence rate in recent years. Animal experiment is one of the important ways to explore pathogenesis and treatment of OA, while induced animal model is the most important part in animal experiment. Intra-articular injection of drugs is a classical method for establishing animal model of OA. Choose of animal should follows the principle of correlation, appropriateness and practicability, injections should perform in accordance with experimental purposes and subject, detections means and evaluation methods also should corresponding to experimental reality. The gold standard of OA animal model and intra-articular injections has not build, need further study.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoarthritis
/
Disease Models, Animal
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
Language:
Zh
Journal:
Zhongguo Gu Shang
Journal subject:
ORTOPEDIA
/
TRAUMATOLOGIA
Year:
2015
Document type:
Article