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Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire.
Scheepers, Cathrine; Shrestha, Ram K; Lambson, Bronwen E; Jackson, Katherine J L; Wright, Imogen A; Naicker, Dshanta; Goosen, Mark; Berrie, Leigh; Ismail, Arshad; Garrett, Nigel; Abdool Karim, Quarraisha; Abdool Karim, Salim S; Moore, Penny L; Travers, Simon A; Morris, Lynn.
Affiliation
  • Scheepers C; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Division of Virology and Communicable Disease Surveillance, School of Pathology, University of the Witwatersrand, Johannesburg
  • Shrestha RK; South African National Bioinformatics Institute, South African Medical Research Council Bioinformatics Unit, University of the Western Cape, Bellville 7535, South Africa;
  • Lambson BE; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Division of Virology and Communicable Disease Surveillance, School of Pathology, University of the Witwatersrand, Johannesburg
  • Jackson KJ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia; Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305;
  • Wright IA; South African National Bioinformatics Institute, South African Medical Research Council Bioinformatics Unit, University of the Western Cape, Bellville 7535, South Africa;
  • Naicker D; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa;
  • Goosen M; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa;
  • Berrie L; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa;
  • Ismail A; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa;
  • Garrett N; Centre for the AIDS Programme of Research in South Africa, KwaZulu-Natal 4013, South Africa; Department of Infectious Diseases, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 4041 Durban, South Africa; and.
  • Abdool Karim Q; Centre for the AIDS Programme of Research in South Africa, KwaZulu-Natal 4013, South Africa; Department of Epidemiology, Columbia University, New York, NY 10032.
  • Abdool Karim SS; Centre for the AIDS Programme of Research in South Africa, KwaZulu-Natal 4013, South Africa; Department of Epidemiology, Columbia University, New York, NY 10032.
  • Moore PL; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Division of Virology and Communicable Disease Surveillance, School of Pathology, University of the Witwatersrand, Johannesburg
  • Travers SA; South African National Bioinformatics Institute, South African Medical Research Council Bioinformatics Unit, University of the Western Cape, Bellville 7535, South Africa;
  • Morris L; Centre for HIV and Sexually Transmitted Infections, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa; Division of Virology and Communicable Disease Surveillance, School of Pathology, University of the Witwatersrand, Johannesburg
J Immunol ; 194(9): 4371-8, 2015 May 01.
Article in En | MEDLINE | ID: mdl-25825450
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genes, Immunoglobulin / HIV Antibodies / HIV Infections / HIV-1 / Antibodies, Neutralizing / Germ Cells Type of study: Prognostic_studies Limits: Adult / Female / Humans Language: En Journal: J Immunol Year: 2015 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genes, Immunoglobulin / HIV Antibodies / HIV Infections / HIV-1 / Antibodies, Neutralizing / Germ Cells Type of study: Prognostic_studies Limits: Adult / Female / Humans Language: En Journal: J Immunol Year: 2015 Document type: Article Country of publication: United States