Taurine Depletion Decreases GRP78 Expression and Downregulates Perk-Dependent Activation of the Unfolded Protein Response.

Jong, Chian Ju; Ito, Takashi; Azuma, Junichi; Schaffer, Stephen

Jong, Chian Ju; Ito, Takashi; Azuma, Junichi; Schaffer, Stephen.

Affiliation

Jong CJ; Department of Pharmacology, College of Medicine, University of South Alabama, Mobile, AL, USA.

Adv Exp Med Biol ; 803: 571-9, 2015.

Article in En | MEDLINE | ID: mdl-25833528

Subject(s)

Heat-Shock Proteins/genetics; Membrane Glycoproteins/genetics; Membrane Transport Proteins/genetics; Taurine/deficiency; Unfolded Protein Response; eIF-2 Kinase/physiology; Aging/physiology; Animals; Down-Regulation/genetics; Endoplasmic Reticulum Chaperone BiP; Gene Expression/drug effects; Heat-Shock Proteins/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction/drug effects; Signal Transduction/genetics; Taurine/pharmacology; Unfolded Protein Response/drug effects; Unfolded Protein Response/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Taurine / Membrane Glycoproteins / EIF-2 Kinase / Unfolded Protein Response / Heat-Shock Proteins Limits: Animals Language: En Journal: Adv Exp Med Biol Year: 2015 Document type: Article Affiliation country: United States

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