SapC-DOPS nanovesicles: a novel targeted agent for the imaging and treatment of glioblastoma.
Oncoscience
; 2(2): 102-110, 2015.
Article
in En
| MEDLINE
| ID: mdl-25859553
ABSTRACT
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor. Classified by the World Health Organization (WHO) as grade IV astrocytoma, GBMs are extremely aggressive, almost always recur, and despite our best efforts, remain incurable. This review describes the traditional treatment approaches that led to moderate successes in GBM patients, discusses standard imaging modalities, and presents data supporting the use of SapC-DOPS, a novel proteoliposomal formulation with tumoricidal activity, as a promising diagnostic imaging tool and an innovative anti-cancer agent against GBM.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Oncoscience
Year:
2015
Document type:
Article
Affiliation country:
United States