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Photodamage attenuation effect by a tetraprenyltoluquinol chromane meroterpenoid isolated from Sargassum muticum.
Balboa, E M; Li, Y-X; Ahn, B-N; Eom, S-H; Domínguez, H; Jiménez, C; Rodríguez, J.
Affiliation
  • Balboa EM; Department of Chemical Engineering, Faculty of Science, Campus Ourense, University of Vigo, Spain; CITI-University of Vigo, Parque Tecnolóxico de Galicia, Ourense, Spain. Electronic address: elenamba@uvigo.es.
  • Li YX; Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea; Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea. Electronic address: lyxycg@qq.com.
  • Ahn BN; Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea; Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea. Electronic address: icetwig@naver.com.
  • Eom SH; Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea; Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea. Electronic address: dalgoo52@gmail.com.
  • Domínguez H; Department of Chemical Engineering, Faculty of Science, Campus Ourense, University of Vigo, Spain; CITI-University of Vigo, Parque Tecnolóxico de Galicia, Ourense, Spain. Electronic address: herminia@uvigo.es.
  • Jiménez C; Centro de Investigacións Científicas Avanzadas (CICA), Departamento Química Fundamental, Facultade de Ciencias, Universidade da Coruña, A Coruña E-15071, Spain. Electronic address: carlos.jimenez@udc.es.
  • Rodríguez J; Centro de Investigacións Científicas Avanzadas (CICA), Departamento Química Fundamental, Facultade de Ciencias, Universidade da Coruña, A Coruña E-15071, Spain. Electronic address: jaime.rodriguez@udc.es.
J Photochem Photobiol B ; 148: 51-58, 2015 Jul.
Article in En | MEDLINE | ID: mdl-25874662
ABSTRACT
A tetraprenyltoluquinol meroterpenoid with a chromane moiety, obtained as an epimeric mixture at C3, was isolated for the first time from the dichloromethane fraction of a methanolic extract from the brown alga Sargassum muticum. The structure has been established by means of spectral methods including NMR spectroscopy and MS and comparison with reported data. The compound showed photodamage attenuation on irradiated cells with UVA light, presented protection against intracellular ROS generation in a degree comparable to retinoic acid (9.1-20.6%) and did not display toxicity against human dermal fibroblast cells.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Terpenes / Sargassum Limits: Humans Language: En Journal: J Photochem Photobiol B Journal subject: BIOLOGIA Year: 2015 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Terpenes / Sargassum Limits: Humans Language: En Journal: J Photochem Photobiol B Journal subject: BIOLOGIA Year: 2015 Document type: Article