Flavour chemicals in electronic cigarette fluids.
Tob Control
; 25(e1): e10-5, 2016 Apr.
Article
in En
| MEDLINE
| ID: mdl-25877377
ABSTRACT
BACKGROUND:
Most e-cigarette liquids contain flavour chemicals. Flavour chemicals certified as safe for ingestion by the Flavor Extracts Manufacturers Association may not be safe for use in e-cigarettes. This study identified and measured flavour chemicals in 30 e-cigarette fluids.METHODS:
Two brands of single-use e-cigarettes were selected and their fluids in multiple flavour types analysed by gas chromatography/mass spectrometry. For the same flavour types, and for selected confectionary flavours (eg, bubble gum and cotton candy), also analysed were convenience samples of e-cigarette fluids in refill bottles from local 'vape' shops and online retailers.RESULTS:
In many liquids, total flavour chemicals were found to be in the â¼1-4% range (10-40â mg/mL); labelled levels of nicotine were in the range of 0.6-2.4% (6 to 24 mg/mL). A significant number of the flavour chemicals were aldehydes, a compound class recognised as 'primary irritants' of mucosal tissue of the respiratory tract. Many of the products contained the same flavour chemicals vanillin and/or ethyl vanillin was found in 17 of the liquids as one of the top three flavour chemicals, and/or at ≥0.5â mg/mL.CONCLUSIONS:
The concentrations of some flavour chemicals in e-cigarette fluids are sufficiently high for inhalation exposure by vaping to be of toxicological concern. Regulatory limits should be contemplated for levels of some of the more worrisome chemicals as well as for total flavour chemical levels. Ingredient labeling should also be required.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Smoking Cessation
/
Nicotinic Agonists
/
Flavoring Agents
/
Electronic Nicotine Delivery Systems
/
Vaping
/
Nicotine
Type of study:
Etiology_studies
/
Risk_factors_studies
Language:
En
Journal:
Tob Control
Journal subject:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Year:
2016
Document type:
Article
Affiliation country:
United States