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Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors.
Gibaja, V; Shen, F; Harari, J; Korn, J; Ruddy, D; Saenz-Vash, V; Zhai, H; Rejtar, T; Paris, C G; Yu, Z; Lira, M; King, D; Qi, W; Keen, N; Hassan, A Q; Chan, H M.
Affiliation
  • Gibaja V; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Shen F; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Harari J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Korn J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Ruddy D; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Saenz-Vash V; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Zhai H; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Rejtar T; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Paris CG; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Yu Z; China Novartis Institutes for BioMedical Research, Shanghai, China.
  • Lira M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • King D; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Qi W; China Novartis Institutes for BioMedical Research, Shanghai, China.
  • Keen N; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Hassan AQ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Chan HM; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
Oncogene ; 35(5): 558-66, 2016 Feb 04.
Article in En | MEDLINE | ID: mdl-25893294
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alleles / Polycomb Repressive Complex 2 / Lymphoma / Mutation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alleles / Polycomb Repressive Complex 2 / Lymphoma / Mutation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2016 Document type: Article Affiliation country: United States Country of publication: United kingdom