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The Core Pattern Analysis on Chinese Herbal Medicine for Sjögren's syndrome: A Nationwide Population-Based Study.
Chang, Ching-Mao; Chu, Hsueh-Ting; Wei, Yau-Huei; Chen, Fang-Pey; Wang, Shengwen; Wu, Po-Chang; Yen, Hung-Rong; Chen, Tzeng-Ji; Chang, Hen-Hong.
Affiliation
  • Chang CM; 1] Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan [2] Graduate Institute of Clinical Medicine, and Graduate Institute of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Chu HT; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Wei YH; 1] Department of Biochemistry and Molecular Biology, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan [2] Department of Medicine, Mackay Medical College, New Taipei, Taiwan.
  • Chen FP; Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Wang S; Cloud Computing and System Integration Division, National Center for High-Performance Computing, Taichung, Taiwan.
  • Wu PC; Division of Rheumatology and Immunology and Department of Education, China Medical University Hospital, Taichung, Taiwan.
  • Yen HR; Research Center for Chinese Medicine and Acupuncture, and School of Chinese Medicine, China Medical University, Taichung, Taiwan.
  • Chen TJ; 1] Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan [2] Institute of Hospital and Health Care Administration, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
  • Chang HH; Research Center for Chinese Medicine and Acupuncture, and School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Sci Rep ; 5: 9541, 2015 04 29.
Article in En | MEDLINE | ID: mdl-25923413
ABSTRACT
This large-scale survey aimed to evaluate frequencies and patterns of Chinese herbal medicine (CHM) used for Sjögren's syndrome (SS) in Taiwan by analyzing the National Health Insurance Research Database (NHIRD) for cases in which CHM was used as an alternative therapy to Western medicine for improving patients' discomforts. We analyzed cases of SS principal diagnosis (ICD-9710.2) with a catastrophic illness certificate (CIC) in traditional Chinese medicine (TCM) outpatient clinics from three cohorts of the Longitudinal Health Insurance Database (LHID) in the NHIRD between 2002 and 2011. CHM prescription patterns for SS were evaluated from claimed visitation files and corresponding prescription files. There were 15,914 SS patients with CIC (SS/CIC), and we found only 130 SS/CIC cases visiting TCM clinics in LHID2000, 133 in LHID2005, and 126 in LHID2010. After removing duplicate data, 366 SS/CIC and 4,867 visits were analyzed. The 50-59 year age group showed the highest ratio (29.51%) in both women and men. "Qi-Ju-Di-Huang-Wan" and "Xuan-Shen" (Scrophularia ningpoensis Hemsl.) was the most commonly used formula and single herb, respectively. "Qi-Ju-Di-Huang-Wan, Gan-Lu-Yin, Xuan-Shen, Mai-Men-Dong (Ophiopogon japonicus (L. f.) Ker-Gawl.), and Sheng-Di-Huang (raw Rehmannia glutinosa Libosch)" were the core pattern prescriptions in treating SS/CIC.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Sjogren's Syndrome Type of study: Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Sci Rep Year: 2015 Document type: Article Affiliation country: Taiwan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Sjogren's Syndrome Type of study: Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Sci Rep Year: 2015 Document type: Article Affiliation country: Taiwan