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Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.
Wong, Yao Liang; Anzola, John V; Davis, Robert L; Yoon, Michelle; Motamedi, Amir; Kroll, Ashley; Seo, Chanmee P; Hsia, Judy E; Kim, Sun K; Mitchell, Jennifer W; Mitchell, Brian J; Desai, Arshad; Gahman, Timothy C; Shiau, Andrew K; Oegema, Karen.
Affiliation
  • Wong YL; Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Anzola JV; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Davis RL; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Yoon M; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Motamedi A; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Kroll A; Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Seo CP; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Hsia JE; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Kim SK; Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Mitchell JW; Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Mitchell BJ; Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Desai A; Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gahman TC; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Shiau AK; Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA. koegema@ucsd.edu ashiau@ucsd.edu.
  • Oegema K; Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093, USA. koegema@ucsd.edu ashiau@ucsd.edu.
Science ; 348(6239): 1155-60, 2015 Jun 05.
Article in En | MEDLINE | ID: mdl-25931445
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfones / Centrioles / Protein Serine-Threonine Kinases / Protein Kinase Inhibitors Limits: Animals / Humans Language: En Journal: Science Year: 2015 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfones / Centrioles / Protein Serine-Threonine Kinases / Protein Kinase Inhibitors Limits: Animals / Humans Language: En Journal: Science Year: 2015 Document type: Article Affiliation country: United States