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Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening.
Holohan, Brody; De Meyer, Tim; Batten, Kimberly; Mangino, Massimo; Hunt, Steven C; Bekaert, Sofie; De Buyzere, Marc L; Rietzschel, Ernst R; Spector, Tim D; Wright, Woodring E; Shay, Jerry W.
Affiliation
  • Holohan B; Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.
  • De Meyer T; Department of Mathematical Modeling, Statistics and Bioinformatics, University of Ghent, Ghent, 9000, Belgium.
  • Batten K; Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, King's College London St. Thomas' Hospital Campus South Wing, Block D, 3rd Floor Westminster Bridge Road, London, SE1 7EH, London, UK.
  • Hunt SC; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, King's College London St. Thomas' Hospital Campus South Wing, Block D, 3rd Floor Westminster Bridge Road, London, SE1 7EH, London, UK.
  • Bekaert S; Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, UT, 84108, USA.
  • De Buyzere ML; Bimetra, Clinical Research Center Ghent, Ghent University Hospital, Ghent, Belgium.
  • Rietzschel ER; Department of Cardiovascular Diseases, Ghent University Hospital, Ghent University, Ghent, Belgium.
  • Spector TD; Department of Cardiovascular Diseases, Ghent University Hospital, Ghent University, Ghent, Belgium.
  • Wright WE; Department of Twin Research and Genetic Epidemiology, King's College London, King's College London St. Thomas' Hospital Campus South Wing, Block D, 3rd Floor Westminster Bridge Road, London, SE1 7EH, London, UK.
  • Shay JW; Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.
Aging Cell ; 14(4): 669-77, 2015 Aug.
Article in En | MEDLINE | ID: mdl-25952108
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Telomere / Telomerase / Inheritance Patterns / Telomere Shortening Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Aging Cell Year: 2015 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Telomere / Telomerase / Inheritance Patterns / Telomere Shortening Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Aging Cell Year: 2015 Document type: Article Affiliation country: United States Country of publication: United kingdom