Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE.

Ayton, Scott; Faux, Noel G; Bush, Ashley I

Ayton, Scott; Faux, Noel G; Bush, Ashley I.

Affiliation

Ayton S; Oxidation Biology Unit, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia.
Faux NG; 1] Bioinformatics Core, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia [2] Cooperative Research Center for Mental Health, Parkville, Victoria 3052, Australia.
Bush AI; 1] Oxidation Biology Unit, The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3052, Australia [2] Cooperative Research Center for Mental Health, Parkville, Victoria 3052, Australia.

Nat Commun ; 6: 6760, 2015 May 19.

Article in En | MEDLINE | ID: mdl-25988319

Subject(s)

Alzheimer Disease/cerebrospinal fluid; Apolipoproteins E/genetics; Ferritins/cerebrospinal fluid; Gene Expression Regulation; Aged; Aged, 80 and over; Atrophy; Brain/metabolism; Cognition; Cognition Disorders/cerebrospinal fluid; Cohort Studies; Databases, Factual; Female; Genotype; Humans; Iron/cerebrospinal fluid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Gene Expression Regulation / Ferritins / Alzheimer Disease Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2015 Document type: Article Affiliation country: Australia

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