[Cholesterol associated to low density lipoproteins (LDL) and vascular risk reduction. Proprotein convertase subtilisin/kexin type 9 (PCSK9): A new therapeutic target].

Guijarro, Carlos; Ruilope, Luis Miguel

[Cholesterol associated to low density lipoproteins (LDL) and vascular risk reduction. Proprotein convertase subtilisin/kexin type 9 (PCSK9): A new therapeutic target]. / Colesterol ligado a lipoproteínas de baja densidad (LDL) y reducción del riesgo vascular. Proproteína convertasa subtilisina / kexina tipo 9 (PCSK9): una nueva diana terapéutica.

Guijarro, Carlos; Ruilope, Luis Miguel.

Affiliation

Guijarro C; Unidad de Medicina Interna, Consulta de Riesgo Vascular, Hospital Universitario Fundación Alcorcón, Universidad Rey Juan Carlos, Madrid, España. Electronic address: cguijarro@fhalcorcon.es.
Ruilope LM; Instituto de Investigación, Unidad de Hipertensión, Hospital Universitario 12 de Octubre, Madrid, España.

Med Clin (Barc) ; 145(2): 67-9, 2015 Jul 20.

Article in Es | MEDLINE | ID: mdl-26004275

Subject(s)

Antibodies, Monoclonal/therapeutic use; Hypercholesterolemia/metabolism; Hyperlipoproteinemias/metabolism; Hypolipidemic Agents/therapeutic use; Lipoproteins, LDL/metabolism; Proprotein Convertases/metabolism; Serine Endopeptidases/metabolism; Antibodies, Monoclonal, Humanized; Biomarkers/metabolism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use; Hypercholesterolemia/drug therapy; Hypercholesterolemia/genetics; Hyperlipoproteinemias/drug therapy; Hyperlipoproteinemias/genetics; Lipoproteins, LDL/genetics; Proprotein Convertase 9; Proprotein Convertases/antagonists & inhibitors; Proprotein Convertases/genetics; Risk Reduction Behavior; Serine Endopeptidases/genetics; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Endopeptidases / Proprotein Convertases / Hypercholesterolemia / Hyperlipoproteinemias / Lipoproteins, LDL / Antibodies, Monoclonal / Hypolipidemic Agents Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: Es Journal: Med Clin (Barc) Year: 2015 Document type: Article Country of publication: Spain

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