Multi-institutional external validation of urinary TWIST1 and NID2 methylation as a diagnostic test for bladder cancer.

Fantony, Joseph J; Abern, Michael R; Gopalakrishna, Ajay; Owusu, Richmond; Jack Tay, Kae; Lance, Raymond S; Inman, Brant A

Fantony, Joseph J; Abern, Michael R; Gopalakrishna, Ajay; Owusu, Richmond; Jack Tay, Kae; Lance, Raymond S; Inman, Brant A.

Affiliation

Fantony JJ; Division of Urology, Duke University Medical Center, Durham, NC.
Abern MR; Department of Urology, University of Illinois Chicago, Chicago, IL.
Gopalakrishna A; Division of Urology, Duke University Medical Center, Durham, NC.
Owusu R; Division of Urology, Duke University Medical Center, Durham, NC.
Jack Tay K; Division of Urology, Duke University Medical Center, Durham, NC.
Lance RS; Division of Urology, Urology of Virginia, Virginia Beach, VA.
Inman BA; Division of Urology, Duke University Medical Center, Durham, NC. Electronic address: brant.inman@duke.edu.

Urol Oncol ; 33(9): 387.e1-6, 2015 Sep.

Article in En | MEDLINE | ID: mdl-26027762

Subject(s)

Biomarkers, Tumor/analysis; Carcinoma, Transitional Cell/diagnosis; Cell Adhesion Molecules/urine; DNA Methylation; Nuclear Proteins/urine; Twist-Related Protein 1/urine; Urinary Bladder Neoplasms/diagnosis; Aged; Area Under Curve; Calcium-Binding Proteins; Carcinoma, Transitional Cell/genetics; Carcinoma, Transitional Cell/urine; Cell Adhesion Molecules/genetics; Cell Adhesion Molecules/metabolism; Cohort Studies; Female; Humans; Likelihood Functions; Male; Middle Aged; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; ROC Curve; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Twist-Related Protein 1/genetics; Twist-Related Protein 1/metabolism; Urinary Bladder Neoplasms/genetics; Urinary Bladder Neoplasms/urine

Key words

Diagnostic test; Epigenetic; Sensitivity; Smoking; Specificity; Urothelial carcinoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Nuclear Proteins / Carcinoma, Transitional Cell / Biomarkers, Tumor / Cell Adhesion Molecules / DNA Methylation / Twist-Related Protein 1 Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Urol Oncol Journal subject: NEOPLASIAS / UROLOGIA Year: 2015 Document type: Article Affiliation country: New Caledonia Country of publication: United States

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