[A prototype of oligonucleotide microarray for detection of pathogens relating to arena- and Filoviridae families].
Bioorg Khim
; 41(1): 54-66, 2015.
Article
in Ru
| MEDLINE
| ID: mdl-26050472
ABSTRACT
A prototype of oligonucleotide microarray for detection of Lassa, Junin, Machupo, Guanarito viruses (Arenaviridae family), Ebola and Marburg viruses (Filoviridae family) was presented. An original approach founded on virus proteins (nucleocapsid protein for Junin, Guanarito, Machupo viruses and RNA-dependent RNA-polymerase for Lassa, Ebola and Marburg viruses) amino acid sequences analysis with subsequent transform of revealed unique peptides into due sets of oligonucleotides was used to design probes for hybridization and primers.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arenaviridae
/
Viral Proteins
/
DNA Primers
/
Oligonucleotide Array Sequence Analysis
/
Ebolavirus
/
Marburgvirus
Type of study:
Diagnostic_studies
Language:
Ru
Journal:
Bioorg Khim
Year:
2015
Document type:
Article