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Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R.
Atsmon, Jacob; Brill-Almon, Einat; Nadri-Shay, Carmit; Chertkoff, Raul; Alon, Sari; Shaikevich, Dimitri; Volokhov, Inna; Haim, Kirsten Y; Bartfeld, Daniel; Shulman, Avidor; Ruderfer, Ilya; Ben-Moshe, Tehila; Shilovitzky, Orit; Soreq, Hermona; Shaaltiel, Yoseph.
Affiliation
  • Atsmon J; Clinical Research Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.
  • Brill-Almon E; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Nadri-Shay C; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Chertkoff R; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Alon S; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Shaikevich D; Clinical Research Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.
  • Volokhov I; Clinical Research Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.
  • Haim KY; Clinical Research Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.
  • Bartfeld D; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Shulman A; Protalix Biotherapeutics, Science Park, Carmiel, Israel. Electronic address: avidors@protalix.com.
  • Ruderfer I; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Ben-Moshe T; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Shilovitzky O; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
  • Soreq H; Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Israel.
  • Shaaltiel Y; Protalix Biotherapeutics, Science Park, Carmiel, Israel.
Toxicol Appl Pharmacol ; 287(3): 202-9, 2015 Sep 15.
Article in En | MEDLINE | ID: mdl-26051873
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Acetylcholinesterase / Organophosphate Poisoning / Antidotes Country/Region as subject: Asia Language: En Journal: Toxicol Appl Pharmacol Year: 2015 Document type: Article Affiliation country: Israel Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Acetylcholinesterase / Organophosphate Poisoning / Antidotes Country/Region as subject: Asia Language: En Journal: Toxicol Appl Pharmacol Year: 2015 Document type: Article Affiliation country: Israel Country of publication: United States