Diagnostic accuracy study of a factor VIII ELISA for detection of factor VIII antibodies in congenital and acquired haemophilia A.

Batty, Paul; Moore, Gary W; Platton, Sean; Maloney, James C; Palmer, Ben; Bowles, Louise; Pasi, K John; Rangarajan, Savita; Hart, Daniel P

Batty, Paul; Moore, Gary W; Platton, Sean; Maloney, James C; Palmer, Ben; Bowles, Louise; Pasi, K John; Rangarajan, Savita; Hart, Daniel P.

Affiliation

Hart DP; Dr. Daniel Hart, Senior Clinical Lecturer and Honorary Consultant in Haemostasis, The Royal London Hospital Haemophilia Centre, The Royal London Hospital, London, E1 1BB, UK, Tel.: +44 203 594 1869, Fax: +44 203 594 1859, E-mail: daniel.hart@bartshealth.nhs.uk.

Thromb Haemost ; 114(4): 804-11, 2015 Oct.

Article in En | MEDLINE | ID: mdl-26063073

Subject(s)

Autoantibodies/blood; Coagulants/immunology; Enzyme-Linked Immunosorbent Assay; Factor VIII/immunology; Hemophilia A/diagnosis; Analysis of Variance; Biomarkers/blood; Coagulants/therapeutic use; Factor VIII/therapeutic use; Hemophilia A/blood; Hemophilia A/drug therapy; Hemophilia A/genetics; Hemophilia A/immunology; Humans; Likelihood Functions; London; Observer Variation; Odds Ratio; Predictive Value of Tests; Reagent Kits, Diagnostic; Reproducibility of Results; Retrospective Studies; Severity of Illness Index

Key words

Bethesda; ELISA; Factor VIII inhibitors; haemophilia A; sensitivity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Factor VIII / Enzyme-Linked Immunosorbent Assay / Coagulants / Hemophilia A Type of study: Diagnostic_studies / Etiology_studies / Evaluation_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: Thromb Haemost Year: 2015 Document type: Article

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