Effectiveness of a Toothpaste with Low Fluoride Content Combined with Trimetaphosphate on Dental Biofilm and Enamel Demineralization in situ.
Caries Res
; 49(4): 394-400, 2015.
Article
in En
| MEDLINE
| ID: mdl-26112176
ABSTRACT
OBJECTIVE:
The aim of the present study was to evaluate in situ whether a toothpaste with low fluoride associated with sodium trimetaphosphate (TMP) would provide similar effect to that of a 1,100 ppm F toothpaste.DESIGN:
This crossover double-blind study consisted of 4 phases (14 days each), during which 10 volunteers wore oral appliances containing 4 enamel bovine blocks. The cariogenic challenge was performed by the application of a 20% sucrose solution (6×/day). The toothpaste treatments (2×/day) were placebo, 500 ppm F, 500 ppm F plus 1% TMP, and 1,100 ppm F. At the end, enamel mineral loss and biofilm composition were analyzed.RESULTS:
The toothpaste with 500 ppm F plus 1% TMP showed the lowest mineral loss (p < 0.05). Regarding the fluoride and calcium concentrations in the enamel and in the biofilm, there were no significant differences between 500 ppm F plus 1% TMP, and 1,100 ppm F toothpastes (p > 0.569), but they were significantly different when compared to toothpaste with 500 ppm F (p < 0.050).CONCLUSION:
The addition of 1% TMP to a low-fluoride toothpaste reduces enamel demineralization in situ similar to a 1,100 ppm F toothpaste.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polyphosphates
/
Toothpastes
/
Cariostatic Agents
/
Tooth Demineralization
/
Biofilms
/
Dental Enamel
/
Fluorides
Type of study:
Clinical_trials
Limits:
Adult
/
Animals
/
Humans
Language:
En
Journal:
Caries Res
Year:
2015
Document type:
Article
Affiliation country:
Brazil