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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.
Egan, Daniel F; Chun, Matthew G H; Vamos, Mitchell; Zou, Haixia; Rong, Juan; Miller, Chad J; Lou, Hua Jane; Raveendra-Panickar, Dhanya; Yang, Chih-Cheng; Sheffler, Douglas J; Teriete, Peter; Asara, John M; Turk, Benjamin E; Cosford, Nicholas D P; Shaw, Reuben J.
Affiliation
  • Egan DF; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Chun MG; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Vamos M; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Zou H; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Rong J; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Miller CJ; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Lou HJ; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Raveendra-Panickar D; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Yang CC; Functional Genomics Core, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Sheffler DJ; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Teriete P; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Asara JM; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Turk BE; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Cosford ND; Cell Death and Survival Networks Research Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: ncosford@sanfordburnham.org.
  • Shaw RJ; Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: shaw@salk.edu.
Mol Cell ; 59(2): 285-97, 2015 Jul 16.
Article in En | MEDLINE | ID: mdl-26118643

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Autophagy / Benzamides / Protein Serine-Threonine Kinases / Intracellular Signaling Peptides and Proteins / Protein Kinase Inhibitors Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Autophagy / Benzamides / Protein Serine-Threonine Kinases / Intracellular Signaling Peptides and Proteins / Protein Kinase Inhibitors Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: United States