Effect of Ramipril on Urinary Protein Excretion in Maintenance Renal Transplant Patients Converted to Sirolimus.

Mandelbrot, D A; Alberú, J; Barama, A; Marder, B A; Silva, H T; Flechner, S M; Flynn, A; Healy, C; Li, H; Tortorici, M A; Schulman, S L

Mandelbrot, D A; Alberú, J; Barama, A; Marder, B A; Silva, H T; Flechner, S M; Flynn, A; Healy, C; Li, H; Tortorici, M A; Schulman, S L.

Affiliation

Mandelbrot DA; Department of Medicine, University of Wisconsin Hospital, Madison, WI.
Alberú J; Transplantation Department, Instituto Nacional de Ciencias Médicas y Nutrición SZ, Mexico City, Mexico.
Barama A; Department of Surgery, University of Montréal, Quebec, Canada.
Marder BA; Internal Medicine/Nephrology, Presbyterian/St Luke's Medical Center, Denver, CO.
Silva HT; Nephrology Division, Hospital do Rim-Universidade Federal de São Paulo, São Paulo, Brazil.
Flechner SM; Glickman Urological and Kidney Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH.
Flynn A; Global Innovative Pharma, Pfizer, Collegeville, PA.
Healy C; Global Innovative Pharma, Pfizer, Collegeville, PA.
Li H; Global Innovative Pharma, Pfizer, Collegeville, PA.
Tortorici MA; Global Innovative Pharma, Pfizer, Collegeville, PA.
Schulman SL; Global Innovative Pharma, Pfizer, Collegeville, PA.

Am J Transplant ; 15(12): 3174-84, 2015 12.

Article in En | MEDLINE | ID: mdl-26176342

Subject(s)

Calcineurin Inhibitors/administration & dosage; Kidney Failure, Chronic/surgery; Kidney Transplantation/adverse effects; Postoperative Complications; Proteinuria/drug therapy; Ramipril/pharmacology; Sirolimus/administration & dosage; Antihypertensive Agents/pharmacology; Double-Blind Method; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection/etiology; Graft Rejection/prevention & control; Graft Survival/drug effects; Humans; Immunosuppressive Agents/therapeutic use; Kidney Function Tests; Male; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Tacrolimus/administration & dosage

Key words

Calcineurin inhibitor (CNI); clinical research/practice; glomerular filtration rate (GFR); immunosuppressant; immunosuppression/immune modulation; kidney (allograft) function/dysfunction; kidney transplantation/nephrology; mechanistic target of rapamycin: sirolimus; rejection: acute, immunosuppressant

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Proteinuria / Kidney Transplantation / Ramipril / Sirolimus / Calcineurin Inhibitors / Kidney Failure, Chronic Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Am J Transplant Journal subject: TRANSPLANTE Year: 2015 Document type: Article Country of publication: United States

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