Combined effects of aging and inflammation on renin-angiotensin  system mediate mitochondrial dysfunction and phenotypic  changes in cardiomyopathies.

Burks, Tyesha N; Marx, Ruth; Powell, Laura; Rucker, Jasma; Bedja, Djahida; Heacock, Elisa; Smith, Barbara J; Foster, D Brian; Kass, David; O'Rourke, Brian; Walston, Jeremy D; Abadir, Peter M

Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies.

Burks, Tyesha N; Marx, Ruth; Powell, Laura; Rucker, Jasma; Bedja, Djahida; Heacock, Elisa; Smith, Barbara J; Foster, D Brian; Kass, David; O'Rourke, Brian; Walston, Jeremy D; Abadir, Peter M.

Affiliation

Burks TN; Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine Baltimore, MD 21205, USA.

Oncotarget ; 6(14): 11979-93, 2015 May 20.

Article in En | MEDLINE | ID: mdl-26221650

Subject(s)

Aging/physiology; Cardiomyopathies/pathology; Inflammation/physiopathology; Mitochondria/pathology; Renin-Angiotensin System/physiology; Animals; Blotting, Western; Cardiomyopathies/physiopathology; Disease Models, Animal; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Phenotype

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Renin-Angiotensin System / Aging / Inflammation / Mitochondria / Cardiomyopathies Limits: Animals Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States

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