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Use of Extracorporeal Membrane Oxygenation to Rescue Patients With Refractory Ventricular Arrhythmia in Acute Myocardial Infarction.
Yeh, Chih-Fan; Wang, Chih-Hsien; Tsai, Pi-Ru; Wu, Cho-Kai; Lin, Yen-Hung; Chen, Yih-Sharng.
Affiliation
  • Yeh CF; From the Department of Internal Medicine (C-FY, C-KW, Y-HL); and Department of Surgery(C-HW, Y-SC, P-RT), National Taiwan University Hospital; and National Taiwan University College of Medicine, Taipei, Taiwan (Y-HL, Y-SC).
Medicine (Baltimore) ; 94(30): e1241, 2015 Jul.
Article in En | MEDLINE | ID: mdl-26222862
Refractory ventricular arrhythmia is a serious problem in acute myocardial infarction (AMI), with an extremely high mortality rate and limited effective treatment. Extracorporeal membrane oxygenation (ECMO) is useful to rescue patients with cardiopulmonary collapse. However, little is known about whether ECMO is a potential rescue technique for patients with refractory ventricular arrhythmia in AMI.We retrospectively analyzed prospectively collected data on patients with AMI and refractory ventricular arrhythmia who underwent ECMO as rescue therapy and the bridge to revascularization from February 2001 to January 2013. Primary endpoint was mortality on index admission, and secondary endpoint was mortality on index admission or advanced brain damage at discharge.A total of 69 (62 men) patients were enrolled in this study. During the index admission, 39 patients (56.5%) met primary endpoint, and 45 patients (65.2%) met secondary endpoint, respectively. In multivariate Cox regression analysis, both the presence of profound anoxic encephalopathy and acute renal failure requiring dialysis were significant predictive factors for both primary and secondary endpoints.ECMO is a feasible rescue therapy and bridge to revascularization in patients with refractory ventricular arrhythmia in acute myocardial infarction. The presence of profound anoxic encephalopathy and acute renal failure requiring dialysis were significant prognostic factors.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Patient Admission / Extracorporeal Membrane Oxygenation / Tachycardia, Ventricular / Myocardial Infarction Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Medicine (Baltimore) Year: 2015 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Patient Admission / Extracorporeal Membrane Oxygenation / Tachycardia, Ventricular / Myocardial Infarction Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Medicine (Baltimore) Year: 2015 Document type: Article Country of publication: United States