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Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation.
Konstantinidis, Diamantis G; Giger, Katie M; Risinger, Mary; Pushkaran, Suvarnamala; Zhou, Ping; Dexheimer, Phillip; Yerneni, Satwica; Andreassen, Paul; Klingmüller, Ursula; Palis, James; Zheng, Yi; Kalfa, Theodosia A.
Affiliation
  • Konstantinidis DG; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Giger KM; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Risinger M; College of Nursing, University of Cincinnati, Cincinnati, OH;
  • Pushkaran S; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Zhou P; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Dexheimer P; Biomedical Informatics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Yerneni S; Biomedical Informatics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Andreassen P; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Klingmüller U; Systems Biology of Signal Transduction, German Cancer Research Center, Center for Molecular Biology Alliance, Heidelberg, Germany; and.
  • Palis J; Department of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, NY.
  • Zheng Y; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
  • Kalfa TA; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH;
Blood ; 126(12): 1473-82, 2015 Sep 17.
Article in En | MEDLINE | ID: mdl-26228485
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Actomyosin / Erythroblasts / Tumor Suppressor Protein p53 / RhoA GTP-Binding Protein / Cytokinesis / Erythropoiesis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Blood Year: 2015 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Actomyosin / Erythroblasts / Tumor Suppressor Protein p53 / RhoA GTP-Binding Protein / Cytokinesis / Erythropoiesis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Blood Year: 2015 Document type: Article Country of publication: United States