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A pharmacologic activator of endothelial KCa channels increases systemic conductance and reduces arterial pressure in an anesthetized pig model.
Mishra, Ramesh C; Mitchell, Jamie R; Gibbons-Kroeker, Carol; Wulff, Heike; Belenkie, Israel; Tyberg, John V; Braun, Andrew P.
Affiliation
  • Mishra RC; Dept. of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; The Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.
  • Mitchell JR; Dept of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
  • Gibbons-Kroeker C; Dept. of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Dept. of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; The Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta,
  • Wulff H; Dept. of Pharmacology, University of California Davis, Davis, CA, USA.
  • Belenkie I; Dept. of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Dept. of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; The Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.
  • Tyberg JV; Dept. of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Dept. of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; The Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary,
  • Braun AP; Dept. of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; The Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada. Electronic address: abraun@ucalgary.ca.
Vascul Pharmacol ; 79: 24-31, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26239885
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Vascular / Benzothiazoles / Intermediate-Conductance Calcium-Activated Potassium Channels / Small-Conductance Calcium-Activated Potassium Channels / Arterial Pressure Limits: Animals Language: En Journal: Vascul Pharmacol Journal subject: ANGIOLOGIA / FARMACOLOGIA Year: 2016 Document type: Article Affiliation country: Canada Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Vascular / Benzothiazoles / Intermediate-Conductance Calcium-Activated Potassium Channels / Small-Conductance Calcium-Activated Potassium Channels / Arterial Pressure Limits: Animals Language: En Journal: Vascul Pharmacol Journal subject: ANGIOLOGIA / FARMACOLOGIA Year: 2016 Document type: Article Affiliation country: Canada Country of publication: United States