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Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma.
Newcomb, Dawn C; Cephus, Jacqueline Yvonne; Boswell, Madison G; Fahrenholz, John M; Langley, Emily W; Feldman, Amy S; Zhou, Weisong; Dulek, Daniel E; Goleniewska, Kasia; Woodward, Kimberly B; Sevin, Carla M; Hamilton, Robert G; Kolls, Jay K; Peebles, R Stokes.
Affiliation
  • Newcomb DC; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: dawn.newcomb@vanderbilt.edu.
  • Cephus JY; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Boswell MG; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Fahrenholz JM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Langley EW; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Feldman AS; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Zhou W; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Dulek DE; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn.
  • Goleniewska K; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Woodward KB; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Sevin CM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
  • Hamilton RG; Department of Medicine and Pathology, Johns Hopkins University School of Medicine, Baltimore, Md.
  • Kolls JK; Department of Pediatrics, Children's Hospital of Pittsburgh, Philadelphia, Pa.
  • Peebles RS; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
J Allergy Clin Immunol ; 136(4): 1025-34.e11, 2015 Oct.
Article in En | MEDLINE | ID: mdl-26242299
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Progesterone / Asthma / Signal Transduction / Gene Expression Regulation / Receptors, Interleukin / Interleukin-17 / MicroRNAs / Estrogens / Interleukin-23 / Th17 Cells Type of study: Risk_factors_studies Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2015 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Progesterone / Asthma / Signal Transduction / Gene Expression Regulation / Receptors, Interleukin / Interleukin-17 / MicroRNAs / Estrogens / Interleukin-23 / Th17 Cells Type of study: Risk_factors_studies Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Allergy Clin Immunol Year: 2015 Document type: Article Country of publication: United States