The immunogenetics of primary biliary cirrhosis: A comprehensive review.

Webb, G J; Siminovitch, K A; Hirschfield, G M

Webb, G J; Siminovitch, K A; Hirschfield, G M.

Affiliation

Webb GJ; NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham, UK.
Siminovitch KA; Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto General Research Institute, and Departments of Immunology and Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Hirschfield GM; NIHR Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham, UK. Electronic address: g.hirschfield@bham.ac.uk.

J Autoimmun ; 64: 42-52, 2015 Nov.

Article in En | MEDLINE | ID: mdl-26250073

Subject(s)

Immunogenetics; Liver Cirrhosis, Biliary/genetics; Liver Cirrhosis, Biliary/immunology; Animals; B-Lymphocyte Subsets/immunology; B-Lymphocyte Subsets/metabolism; Epigenesis, Genetic; Epistasis, Genetic; Gene Expression Regulation; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; HLA Antigens/genetics; HLA Antigens/immunology; Humans; Liver Cirrhosis, Biliary/diagnosis; Liver Cirrhosis, Biliary/metabolism; Liver Cirrhosis, Biliary/therapy; Phenotype; Selection, Genetic; Signal Transduction; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/metabolism

Key words

Animal models; CD4+ T cell; Genome-wide association study; HLA; Immunochip; Regulatory T cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunogenetics / Liver Cirrhosis, Biliary Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2015 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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