Do not scratch that mole!
Trends Immunol
; 36(9): 503-4, 2015 Sep.
Article
in En
| MEDLINE
| ID: mdl-26254146
ABSTRACT
Nevi harbor some of the same oncogene mutations that also drive malign melanoma. Further tumor promoting events are required to unleash their carcinogenic potential. Using zebrafish whose melanocytes overexpress an HRAS-oncogene, a new study reports that injury induces melanoma, possibly through recruitment of neutrophils that trigger proliferation of preneoplastic melanocytes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Precancerous Conditions
/
Wounds and Injuries
/
Zebrafish
/
Melanoma
/
Neoplasms, Experimental
Limits:
Animals
/
Humans
Language:
En
Journal:
Trends Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2015
Document type:
Article
Affiliation country:
United States