Your browser doesn't support javascript.
loading
Cholestatic hepatitis C after chemotherapy containing rituximab in diffuse large B cell lymphoma.
Pellicelli, Adriano M; D'Ambrosio, Cecilia; Dessanti, Maria L; Villani, Roberto; Fondacaro, Lucia; Miglioresi, Lucia; Grillo, Lucia R; Andreoli, Arnaldo.
Affiliation
  • Pellicelli AM; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • D'Ambrosio C; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • Dessanti ML; Department of Hematology Istituti Fisoterapici Ospedalieri, Italy.
  • Villani R; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • Fondacaro L; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • Miglioresi L; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • Grillo LR; Department of Pathology, Azienda Ospedaliera San Camillo Forlanini, Italy.
  • Andreoli A; Liver Unit, Azienda Ospedaliera San Camillo Forlanini, Italy.
Ann Hepatol ; 14(5): 756-61, 2015.
Article in En | MEDLINE | ID: mdl-26256907
Rituximab is a chimeric anti-CD20 monoclonal antibody that is a widely used for the treatment of B cells non-Hodgkin lymphoma. The use of chemotherapy regimens containing rituximab in HCV-positive patients with non-Hodgkin lymphoma has been associated with liver dysfunction, but no cases of cholestatic hepatitis C were described. To our knowledge, this is the first case of cholestatic hepatitis C in an HCV-positive patient with diffuse large B-cell lymphoma describes in the literature. We discuss the pathogenetic mechanisms underlying this severe form of hepatitis and describe its evolution after antiviral treatment.
Subject(s)
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Virus Activation / Antineoplastic Combined Chemotherapy Protocols / Cholestasis / Lymphoma, Large B-Cell, Diffuse / Hepatitis C / Hepacivirus / Rituximab Type of study: Diagnostic_studies Limits: Aged / Humans / Male Language: En Journal: Ann Hepatol Journal subject: GASTROENTEROLOGIA Year: 2015 Document type: Article Affiliation country: Italy Country of publication: Mexico
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Virus Activation / Antineoplastic Combined Chemotherapy Protocols / Cholestasis / Lymphoma, Large B-Cell, Diffuse / Hepatitis C / Hepacivirus / Rituximab Type of study: Diagnostic_studies Limits: Aged / Humans / Male Language: En Journal: Ann Hepatol Journal subject: GASTROENTEROLOGIA Year: 2015 Document type: Article Affiliation country: Italy Country of publication: Mexico