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N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Nuti, Elisa; Cantelmo, Anna Rita; Gallo, Cristina; Bruno, Antonino; Bassani, Barbara; Camodeca, Caterina; Tuccinardi, Tiziano; Vera, Laura; Orlandini, Elisabetta; Nencetti, Susanna; Stura, Enrico A; Martinelli, Adriano; Dive, Vincent; Albini, Adriana; Rossello, Armando.
Affiliation
  • Nuti E; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
  • Cantelmo AR; Science and Technological Park, IRCCS MultiMedica , via Fantoli 16/15, 20138 Milan, Italy.
  • Gallo C; Laboratory of Translational Research, IRCCS Arcispedale Santa Maria Nuova , viale Risorgimento 80, 42121 Reggio Emilia, Italy.
  • Bruno A; Science and Technological Park, IRCCS MultiMedica , via Fantoli 16/15, 20138 Milan, Italy.
  • Bassani B; Science and Technological Park, IRCCS MultiMedica , via Fantoli 16/15, 20138 Milan, Italy.
  • Camodeca C; Division of Immunology, Transplants and Infectious Diseases, IRCCS San Raffaele , via Olgettina 60, 20132 Milano, Italy.
  • Tuccinardi T; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
  • Vera L; CEA, iBiTec-S, Service d'Ingenierie Moleculaire des Proteines (SIMOPRO), CE-Saclay 91191 Gif sur Yvette Cedex, France.
  • Orlandini E; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
  • Nencetti S; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
  • Stura EA; CEA, iBiTec-S, Service d'Ingenierie Moleculaire des Proteines (SIMOPRO), CE-Saclay 91191 Gif sur Yvette Cedex, France.
  • Martinelli A; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
  • Dive V; CEA, iBiTec-S, Service d'Ingenierie Moleculaire des Proteines (SIMOPRO), CE-Saclay 91191 Gif sur Yvette Cedex, France.
  • Albini A; Laboratory of Translational Research, IRCCS Arcispedale Santa Maria Nuova , viale Risorgimento 80, 42121 Reggio Emilia, Italy.
  • Rossello A; Dipartimento di Farmacia, Università di Pisa , via Bonanno 6, 56126 Pisa, Italy.
J Med Chem ; 58(18): 7224-40, 2015 Sep 24.
Article in En | MEDLINE | ID: mdl-26263024
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Angiogenesis Inhibitors / Matrix Metalloproteinase Inhibitors / Hydroxamic Acids Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2015 Document type: Article Affiliation country: Italy Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Angiogenesis Inhibitors / Matrix Metalloproteinase Inhibitors / Hydroxamic Acids Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2015 Document type: Article Affiliation country: Italy Country of publication: United States