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AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages.
Six, E; Lagresle-Peyrou, C; Susini, S; De Chappedelaine, C; Sigrist, N; Sadek, H; Chouteau, M; Cagnard, N; Fontenay, M; Hermine, O; Chomienne, C; Reynier, P; Fischer, A; André-Schmutz, I; Gueguen, N; Cavazzana, M.
Affiliation
  • Six E; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Lagresle-Peyrou C; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Susini S; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • De Chappedelaine C; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Sigrist N; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Sadek H; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Chouteau M; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Cagnard N; SFR Necker, Plateforme de bioinformatique, Paris Descartes-Sorbonne Paris Cité University, Paris, France.
  • Fontenay M; Department of Immunology and Hematology, Cochin Institute, INSERM U1016, Paris, France.
  • Hermine O; 1] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France [2] Department of Adult Hematology, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
  • Chomienne C; 1] Service de Biologie Cellulaire, Hopital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France [2] INSERM UMRS 940, Diderot - Sorbonne Paris Cité University, Paris, France.
  • Reynier P; UMR CNRS6214, INSERM 1083, Département de Biochimie et Génétique, Centre Hospitalier Universitaire, Angers, France.
  • Fischer A; 1] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France [2] Pediatric Immunology-Hematology and Rhumatology Department, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France [3] Collège de France, Paris, France.
  • André-Schmutz I; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.
  • Gueguen N; UMR CNRS6214, INSERM 1083, Département de Biochimie et Génétique, Centre Hospitalier Universitaire, Angers, France.
  • Cavazzana M; 1] Laboratory of Human Lymphohematopoiesis, INSERM UMR 1163, Paris, France [2] Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France [3] Biotherapy Department, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France [4] Biotherapy Clinical Investig
Cell Death Dis ; 6: e1856, 2015 Aug 13.
Article in En | MEDLINE | ID: mdl-26270350
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Lymphocytes / Adenylate Kinase / Severe Combined Immunodeficiency / Leukopenia / Mitochondria / Neutrophils Limits: Humans Language: En Journal: Cell Death Dis Year: 2015 Document type: Article Affiliation country: France Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Lymphocytes / Adenylate Kinase / Severe Combined Immunodeficiency / Leukopenia / Mitochondria / Neutrophils Limits: Humans Language: En Journal: Cell Death Dis Year: 2015 Document type: Article Affiliation country: France Country of publication: United kingdom