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Comparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database).
Singh, Vikas; Badheka, Apurva O; Patel, Samir V; Patel, Nileshkumar J; Thakkar, Badal; Patel, Nilay; Arora, Shilpkumar; Patel, Nish; Patel, Achint; Savani, Chirag; Ghatak, Abhijit; Panaich, Sidakpal S; Jhamnani, Sunny; Deshmukh, Abhishek; Chothani, Ankit; Sonani, Rajesh; Patel, Aashay; Bhatt, Parth; Dave, Abhishek; Bhimani, Ronak; Mohamad, Tamam; Grines, Cindy; Cleman, Michael; Forrest, John K; Mangi, Abeel.
Affiliation
  • Singh V; Cardiology Department, University of Miami Miller School of Medicine, Miami, Florida.
  • Badheka AO; Interventional Cardiology Department, The Everett Clinic, Everett, Washington. Electronic address: abadheka@everettclinic.com.
  • Patel SV; Internal Medicine Department, Western Reserve Health System, Youngstown, Ohio.
  • Patel NJ; Cardiology Department, University of Miami Miller School of Medicine, Miami, Florida.
  • Thakkar B; Epidemiology Department, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana.
  • Patel N; Internal Medicine Department, Saint Peter's University Hospital, New Brunswick, New Jersey.
  • Arora S; Internal Medicine Department, Mount Sinai St. Luke's Roosevelt Hospital, New York, New York.
  • Patel N; Cardiology Department, University of Miami Miller School of Medicine, Miami, Florida.
  • Patel A; Public Health Department, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Savani C; Epidemiology Department, New York Medical College, Valhalla, New York.
  • Ghatak A; Cardiology Department, University of Miami Miller School of Medicine, Miami, Florida.
  • Panaich SS; Cardiology Department, Detroit Medical Center, Detroit, Michigan.
  • Jhamnani S; Interventional Cardiology Department, The Everett Clinic, Everett, Washington.
  • Deshmukh A; Cardiology Department, Mayo Clinic, Rochester, Minnesota.
  • Chothani A; Internal Medicine Department, MedStar Washington Hospital Center, Washington, DC.
  • Sonani R; Internal Medicine Department, Emory University School of Medicine, Atlanta, Georgia.
  • Patel A; Internal Medicine Department, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania.
  • Bhatt P; Internal Medicine Department, Saint Peter's University Hospital, New Brunswick, New Jersey.
  • Dave A; Public Health Department, Texas A&M Medical Centre, College Station, Texas.
  • Bhimani R; Internal Medicine Department, St. Vincent Charity Medical Centre, Cleveland, Ohio.
  • Mohamad T; Cardiology Department, Detroit Medical Center, Detroit, Michigan.
  • Grines C; Cardiology Department, Detroit Medical Center, Detroit, Michigan.
  • Cleman M; Cardiology Department, Yale School of Medicine, New Haven, Connecticut.
  • Forrest JK; Cardiology Department, Yale School of Medicine, New Haven, Connecticut.
  • Mangi A; Cardiology Department, Yale School of Medicine, New Haven, Connecticut.
Am J Cardiol ; 116(8): 1229-36, 2015 Oct 15.
Article in En | MEDLINE | ID: mdl-26297512
We hypothesized that the availability of a transcatheter aortic valve implantation (TAVI) program in hospitals impacts the overall management of patients with aortic valve disease and hence may also improve postprocedural outcomes of conventional surgical aortic valve replacement (SAVR). The aim of the present study was to compare the inhospital outcomes of SAVR in centers with versus without availability of a TAVI program in an unrestricted large nationwide patient population >50 years of age. SAVRs performed on patients aged >50 years were identified from the Nationwide Inpatient Sample (NIS) for the years 2011 and 2012 using the International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes. SAVR cases were divided into 2 categories: those performed at hospitals with a TAVI program (SAVR-TAVI) and those without (SAVR-non-TAVI). A total of 9,674 SAVR procedures were identified: 4,526 (46.79%) in the SAVR-TAVI group and 5,148 (53.21%) in SAVR-non-TAVI group. The mean age of the study population was 70.2 ± 0.1 years with majority (53%) of the patients aged >70 years. The mean Charlson's co-morbidity score for patients in SAVR-TAVI group was greater (greater percentage of patients were aged >80 years, had hypertension, congestive heart failure, renal failure, and peripheral arterial disease) than that of patients in SAVR-non-TAVI group (1.6 vs 1.4, p <0.001). The propensity score matching analysis showed a statistically significant lower inhospital mortality (1.25% vs 1.72%, p = 0.001) and complications rate (35.6% vs 37.3%, p = 0.004) in SAVR-TAVI group compared to SAVR-non-TAVI group. The mean length of hospital stay was similar in the 2 groups the cost of hospitalization was higher in the SAVR-TAVI group ($43,894 ± 483 vs $41,032 ± 473, p <0.0001). Having a TAVI program was a significant predictor of reduced mortality and complications rate after SAVR in multivariate analysis. In conclusion, this largest direct comparative analysis demonstrates that SAVRs performed in centers with a TAVI program are associated with significantly lower mortality and complications rates compared to those performed in centers without a TAVI program.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiac Care Facilities / Transcatheter Aortic Valve Replacement / Heart Defects, Congenital / Heart Valve Diseases Type of study: Diagnostic_studies / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Am J Cardiol Year: 2015 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiac Care Facilities / Transcatheter Aortic Valve Replacement / Heart Defects, Congenital / Heart Valve Diseases Type of study: Diagnostic_studies / Prognostic_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Am J Cardiol Year: 2015 Document type: Article Country of publication: United States