Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls.

Humphries, Edward S A; Dart, Caroline

Humphries, Edward S A; Dart, Caroline.

Affiliation

Humphries ES; Institute of Integrative Biology, University of Liverpool, UK.
Dart C; Institute of Integrative Biology, University of Liverpool, UK c.dart@liv.ac.uk.

J Biomol Screen ; 20(9): 1055-73, 2015 Oct.

Article in En | MEDLINE | ID: mdl-26303307

Subject(s)

Cardiovascular Agents/therapeutic use; Cardiovascular Diseases/drug therapy; Nervous System Diseases/drug therapy; Potassium Channel Blockers/therapeutic use; Potassium Channels/physiology; Animals; Cardiovascular Agents/pharmacology; Cardiovascular Diseases/metabolism; Humans; Myocardium/metabolism; Nervous System Diseases/metabolism; Neurons/metabolism; Potassium Channel Blockers/pharmacology

Key words

K+ channels; cardiac; channelopathies; drug development; ion channels; neuronal; review; vascular

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiovascular Agents / Cardiovascular Diseases / Potassium Channels / Potassium Channel Blockers / Nervous System Diseases Limits: Animals / Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: United kingdom

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