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Effectiveness of bronchial thermoplasty in severe asthma in 'real life' patients compared with those recruited to clinical trials in the same centre.
Bicknell, Stephen; Chaudhuri, Rekha; Lee, Nicola; Shepherd, Malcolm; Spears, Mark; Pitman, Nick; Cameron, Euan; Cowan, Douglas; Nixon, Julie; Thompson, Joyce; McSharry, Charles; Thomson, Neil C.
Affiliation
  • Bicknell S; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Chaudhuri R; Department of Respiratory Medicine, Gartnavel General Hospital, Glasgow G12 OYN, UK rekhachaudhuri@yahoo.com.
  • Lee N; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Shepherd M; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Spears M; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Pitman N; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Cameron E; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Cowan D; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Nixon J; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • Thompson J; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
  • McSharry C; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
  • Thomson NC; Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Ther Adv Respir Dis ; 9(6): 267-71, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26307767
ABSTRACT
Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in 'real life' patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Bronchi / Bronchoscopy / Clinical Trials as Topic / Catheter Ablation / Patient Selection Type of study: Diagnostic_studies / Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Ther Adv Respir Dis Journal subject: PNEUMOLOGIA / TERAPEUTICA Year: 2015 Document type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Bronchi / Bronchoscopy / Clinical Trials as Topic / Catheter Ablation / Patient Selection Type of study: Diagnostic_studies / Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Ther Adv Respir Dis Journal subject: PNEUMOLOGIA / TERAPEUTICA Year: 2015 Document type: Article Affiliation country: United kingdom