Targeting Mechanism of a Novel Liver-targeting Interferon IFN-CSP Involves Liver Heparan Sulfate Proteoglycan.

Lu, Xuemei; Wang, Jie; Jin, Xiaobao; Huang, Yanting; Zeng, Wenting; Zhu, Jiayong

Lu, Xuemei; Wang, Jie; Jin, Xiaobao; Huang, Yanting; Zeng, Wenting; Zhu, Jiayong.

Affiliation

Lu X; luxuemei605@163.com.
Zhu J; School of Basic Courses, Guangdong Pharmaceutical University, 280 Wai Huan Dong Road, Guangzhou Higher Education Mega Center, Guangzhou 510006, People's Republic of China. zhujiayong1020@163.com.

Curr Drug Deliv ; 13(4): 528-33, 2016.

Article in En | MEDLINE | ID: mdl-26310618

Subject(s)

Heparan Sulfate Proteoglycans/metabolism; Interferon-alpha/administration & dosage; Liver/drug effects; Protozoan Proteins/administration & dosage; Animals; Binding Sites; Hep G2 Cells; Humans; Interferon alpha-2; Interferon-alpha/chemistry; Liver/metabolism; Mice; Mice, Inbred BALB C; Plasmodium/chemistry; Protozoan Proteins/chemistry; Recombinant Proteins/administration & dosage; Recombinant Proteins/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Protozoan Proteins / Interferon-alpha / Heparan Sulfate Proteoglycans / Liver Limits: Animals / Humans Language: En Journal: Curr Drug Deliv Journal subject: FARMACIA / FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2016 Document type: Article

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