Amyotrophic Lateral Sclerosis/physiopathology; Central Nervous System/physiopathology; Disease Models, Animal; Motor Neurons/metabolism; Amyotrophic Lateral Sclerosis/drug therapy; Amyotrophic Lateral Sclerosis/genetics; Amyotrophic Lateral Sclerosis/metabolism; Animals; Central Nervous System/drug effects; Central Nervous System/enzymology; DNA-Binding Proteins/agonists; DNA-Binding Proteins/antagonists & inhibitors; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Endoplasmic Reticulum Stress/drug effects; Humans; Mice; Mice, Knockout; Mice, Neurologic Mutants; Mice, Transgenic; Motor Neurons/drug effects; Motor Neurons/enzymology; Mutation; Nerve Tissue Proteins/antagonists & inhibitors; Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/metabolism; Promoter Regions, Genetic/drug effects; RNA Processing, Post-Transcriptional/drug effects; Rats; Rats, Mutant Strains; Rats, Transgenic; Superoxide Dismutase/chemistry; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism; Superoxide Dismutase-1

Amyotrophic Lateral Sclerosis; RNA processing alterations; aberrant protein homeostasis; glia; motor neuron; rodent models