Curcumin Induces Pancreatic Adenocarcinoma Cell Death Via Reduction of the Inhibitors of Apoptosis.

Díaz Osterman, Carlos J; Gonda, Amber; Stiff, TessaRae; Sigaran, Ulysses; Valenzuela, Malyn May Asuncion; Ferguson Bennit, Heather R; Moyron, Ron B; Khan, Salma; Wall, Nathan R

Díaz Osterman, Carlos J; Gonda, Amber; Stiff, TessaRae; Sigaran, Ulysses; Valenzuela, Malyn May Asuncion; Ferguson Bennit, Heather R; Moyron, Ron B; Khan, Salma; Wall, Nathan R.

Affiliation

Díaz Osterman CJ; From the *Department of Biochemistry, and Department of Anatomy, Center for Health Disparity and Molecular Medicine, Loma Linda University, Loma Linda, CA.

Pancreas ; 45(1): 101-9, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26348467

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis/drug effects; Carcinoma, Pancreatic Ductal/drug therapy; Curcumin/pharmacology; Inhibitor of Apoptosis Proteins/metabolism; Pancreatic Neoplasms/drug therapy; Antineoplastic Agents, Phytogenic/metabolism; Carcinoma, Pancreatic Ductal/genetics; Carcinoma, Pancreatic Ductal/metabolism; Carcinoma, Pancreatic Ductal/pathology; Cell Line, Tumor; Cell Shape/drug effects; Cell Survival/drug effects; Curcumin/metabolism; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins/genetics; Pancreatic Neoplasms/genetics; Pancreatic Neoplasms/metabolism; Pancreatic Neoplasms/pathology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Apoptosis / Curcumin / Carcinoma, Pancreatic Ductal / Inhibitor of Apoptosis Proteins / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Pancreas Journal subject: GASTROENTEROLOGIA Year: 2016 Document type: Article Affiliation country: Canada

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