Bevacizumab treatment for symptomatic spinal ependymomas in neurofibromatosis type 2.

Farschtschi, S; Merker, V L; Wolf, D; Schuhmann, M; Blakeley, J; Plotkin, S R; Hagel, C; Mautner, V F

Farschtschi, S; Merker, V L; Wolf, D; Schuhmann, M; Blakeley, J; Plotkin, S R; Hagel, C; Mautner, V F.

Affiliation

Farschtschi S; Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Merker VL; Massachusetts General Hospital, Pappas Center for Neuro Oncology, Boston, MA, USA.
Wolf D; Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD, USA.
Schuhmann M; Department of Neurosurgery, University Medical Center Tübingen, Tübingen, Germany.
Blakeley J; Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD, USA.
Plotkin SR; Massachusetts General Hospital, Pappas Center for Neuro Oncology, Boston, MA, USA.
Hagel C; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Mautner VF; Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Acta Neurol Scand ; 133(6): 475-80, 2016 Jun.

Article in En | MEDLINE | ID: mdl-26369495

Subject(s)

Angiogenesis Inhibitors/therapeutic use; Bevacizumab/therapeutic use; Ependymoma/drug therapy; Neurofibromatosis 2/drug therapy; Spinal Cord Neoplasms/drug therapy; Adolescent; Adult; Angiogenesis Inhibitors/adverse effects; Bevacizumab/adverse effects; Ependymoma/complications; Ependymoma/pathology; Female; Humans; Male; Neurofibromatosis 2/complications; Neurofibromatosis 2/pathology; Spinal Cord Neoplasms/pathology; Vascular Endothelial Growth Factor Receptor-1/genetics; Vascular Endothelial Growth Factor Receptor-1/metabolism; Vascular Endothelial Growth Factor Receptor-2

Key words

bevacizumab; ependymoma; neurofibromatosis; neurofibromatosis type 2; vascular endothelial growth factor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Neoplasms / Neurofibromatosis 2 / Angiogenesis Inhibitors / Ependymoma / Bevacizumab Type of study: Diagnostic_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Acta Neurol Scand Year: 2016 Document type: Article Affiliation country: Germany Country of publication: Denmark

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