Involvement of p53 in insulin-like growth factor binding protein-3 regulation in the breast cancer cell response to DNA damage.

Marzec, Kamila A; Lin, Mike Z; Martin, Janet L; Baxter, Robert C

Marzec, Kamila A; Lin, Mike Z; Martin, Janet L; Baxter, Robert C.

Affiliation

Marzec KA; Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, NSW, Australia.
Lin MZ; Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, NSW, Australia.
Martin JL; Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, NSW, Australia.
Baxter RC; Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, NSW, Australia.

Oncotarget ; 6(29): 26583-98, 2015 Sep 29.

Article in En | MEDLINE | ID: mdl-26378048

Subject(s)

Breast Neoplasms/metabolism; DNA Damage; Gene Expression Regulation, Neoplastic; Insulin-Like Growth Factor Binding Protein 3/metabolism; Tumor Suppressor Protein p53/metabolism; Antineoplastic Agents/chemistry; Apoptosis; Breast Neoplasms/genetics; Caspase 3/metabolism; Cell Line, Tumor; Doxorubicin/chemistry; Etoposide/chemistry; Female; Gene Silencing; Humans; Membrane Proteins/metabolism; Mutation; Nerve Tissue Proteins/metabolism; RNA, Small Interfering/metabolism; Real-Time Polymerase Chain Reaction

Key words

DNA damage; breast cancer; chemotherapy; insulin-like growth factor binding protein-3 (IGFBP-3); p53

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Breast Neoplasms / Gene Expression Regulation, Neoplastic / Tumor Suppressor Protein p53 / Insulin-Like Growth Factor Binding Protein 3 Limits: Female / Humans Language: En Journal: Oncotarget Year: 2015 Document type: Article Affiliation country: Australia Country of publication: United States

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