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The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression.
Hung, T; Pratt, G A; Sundararaman, B; Townsend, M J; Chaivorapol, C; Bhangale, T; Graham, R R; Ortmann, W; Criswell, L A; Yeo, G W; Behrens, T W.
Affiliation
  • Hung T; Genentech, South San Francisco, CA 94080, USA. behrens.tim@gene.com hungt2@gene.com geneyeo@ucsd.edu.
  • Pratt GA; Department of Cellular and Molecular Medicine, Institute for Genomic Medicine, Stem Cell Program, University of California at San Diego, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA.
  • Sundararaman B; Department of Cellular and Molecular Medicine, Institute for Genomic Medicine, Stem Cell Program, University of California at San Diego, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA.
  • Townsend MJ; Genentech, South San Francisco, CA 94080, USA.
  • Chaivorapol C; Genentech, South San Francisco, CA 94080, USA.
  • Bhangale T; Genentech, South San Francisco, CA 94080, USA.
  • Graham RR; Genentech, South San Francisco, CA 94080, USA.
  • Ortmann W; Genentech, South San Francisco, CA 94080, USA.
  • Criswell LA; Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, CA 94143, USA.
  • Yeo GW; Department of Cellular and Molecular Medicine, Institute for Genomic Medicine, Stem Cell Program, University of California at San Diego, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA. Department of Physiology, National University of Singapore,
  • Behrens TW; Genentech, South San Francisco, CA 94080, USA. behrens.tim@gene.com hungt2@gene.com geneyeo@ucsd.edu.
Science ; 350(6259): 455-9, 2015 Oct 23.
Article in En | MEDLINE | ID: mdl-26382853
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleoproteins / Autoantigens / Sjogren's Syndrome / Gene Expression Regulation / Alu Elements / RNA, Small Cytoplasmic / Lupus Erythematosus, Systemic Limits: Humans Language: En Journal: Science Year: 2015 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleoproteins / Autoantigens / Sjogren's Syndrome / Gene Expression Regulation / Alu Elements / RNA, Small Cytoplasmic / Lupus Erythematosus, Systemic Limits: Humans Language: En Journal: Science Year: 2015 Document type: Article Country of publication: United States