Stereoselective Formation of Substituted 1,3-Dioxolanes through a Three-Component Assembly during the Oxidation of Alkenes with Hypervalent Iodine(III).
Molecules
; 20(9): 17041-57, 2015 Sep 17.
Article
in En
| MEDLINE
| ID: mdl-26393548
ABSTRACT
Stereoselective formation of substituted 1,3-dioxolanes was achieved through an assembly of three components alkene, carboxylic acid and silyl enol ether. The reaction proceeded via stereospecific generation of a 1,3-dioxolan-2-yl cation intermediate during oxidation of alkene substrates with hypervalent iodine. The stereoselective trapping of the cation intermediate with silyl enol ether completed the formation of the dioxolane product.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dioxolanes
/
Alkenes
/
Iodine
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2015
Document type:
Article
Affiliation country:
Japan