[Genetic Association of ADRA2A and ADRB3 Genes with Metabolic Syndrome among the Tatars].
Genetika
; 51(7): 830-4, 2015 Jul.
Article
in Ru
| MEDLINE
| ID: mdl-26410938
ABSTRACT
An association study was performed for genetic polymorphisms in ADRB3 (rs4994) and ADRA2A (rs1800544, rs553668) genes to estimate their effect on quantitative parameters, including glucose, insulin, and HOMA-IR index in women from the Tatar population of Russia. It has been shown that CT and CC are associated with metabolic syndrome and increased insulin. It was shown that ADRA2A (rs1800544) gene polymorphism was associated with high levels of insulin and an increased HOMA-IR index in GG- and GC-genotype carriers.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Receptors, Adrenergic, alpha-2
/
Polymorphism, Single Nucleotide
/
Receptors, Adrenergic, beta-3
/
Metabolic Syndrome
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
Country/Region as subject:
Asia
/
Europa
Language:
Ru
Journal:
Genetika
Year:
2015
Document type:
Article