Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition.

Willemse, Hermia; Theodoratos, Angelo; Smith, Paul N; Dulhunty, Angela F

Willemse, Hermia; Theodoratos, Angelo; Smith, Paul N; Dulhunty, Angela F.

Affiliation

Willemse H; John Curtin School of Medical Research, Australian National University, Acton, ACT, 2600, Australia. Hermia.Willemse@canberra.edu.au.
Theodoratos A; John Curtin School of Medical Research, Australian National University, Acton, ACT, 2600, Australia. angelo.theodoratos@anu.edu.au.
Smith PN; Trauma and Orthopaedic Research Unit, Canberra Hospital, Building 6, Level 1, P.O. Box 11, Woden, ACT, 2606, Australia. psmith@orthoact.com.au.
Dulhunty AF; John Curtin School of Medical Research, Australian National University, Acton, ACT, 2600, Australia. angela.dulhunty@anu.edu.au.

Pflugers Arch ; 468(2): 269-78, 2016 Feb.

Article in En | MEDLINE | ID: mdl-26438192

Subject(s)

Muscle Fibers, Skeletal/metabolism; Ryanodine Receptor Calcium Release Channel/metabolism; Aged; Aged, 80 and over; Female; Gene Expression Regulation, Developmental; Humans; Leg/anatomy & histology; Leg/growth & development; Male; Middle Aged; Muscle Fibers, Skeletal/cytology; Myosin Heavy Chains/genetics; Myosin Heavy Chains/metabolism; Protein Isoforms/genetics; Protein Isoforms/metabolism; Ryanodine Receptor Calcium Release Channel/genetics

Key words

ASI splice variants; Aging; Fiber types; Human skeletal muscle; Ryanodine receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscle Fibers, Skeletal / Ryanodine Receptor Calcium Release Channel Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Pflugers Arch Year: 2016 Document type: Article Affiliation country: Australia Country of publication: Germany

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