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Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway.
Surmeli, Zeki; Gursoy, Pinar; Erdogan, Atike Pinar; Bozkurt, Emir; Atmaca, Harika; Uzunoglu, Selim; Sezgin, Canfeza; Sanli, Ulus Ali; Uslu, Ruchan; Karaca, Burcak.
Affiliation
  • Surmeli Z; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Gursoy P; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Erdogan AP; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Bozkurt E; Section of Molecular Biology, Department of Biology, Faculty of Science and Letters, Celal Bayar University, 45140, Muradiye, Manisa, Turkey.
  • Atmaca H; Section of Molecular Biology, Department of Biology, Faculty of Science and Letters, Celal Bayar University, 45140, Muradiye, Manisa, Turkey.
  • Uzunoglu S; Section of Molecular Biology, Department of Biology, Faculty of Science and Letters, Celal Bayar University, 45140, Muradiye, Manisa, Turkey.
  • Sezgin C; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Sanli UA; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Uslu R; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey.
  • Karaca B; Division of Medical Oncology, Tulay Aktas Oncology Hospital, School of Medicine, Ege University, 35100, Bornova, Izmir, Turkey. burcak.karaca@ege.edu.tr.
Tumour Biol ; 37(3): 3665-73, 2016 Mar.
Article in En | MEDLINE | ID: mdl-26462835
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Apoptosis / Phosphatidylinositol 3-Kinases / Diphosphonates / Enzyme Inhibitors / Proto-Oncogene Proteins c-akt / Imidazoles Limits: Female / Humans Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Turkey Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Apoptosis / Phosphatidylinositol 3-Kinases / Diphosphonates / Enzyme Inhibitors / Proto-Oncogene Proteins c-akt / Imidazoles Limits: Female / Humans Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Turkey Country of publication: Netherlands