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Atrioventricular septal defect: From embryonic development to long-term follow-up.
Calkoen, Emmeline E; Hazekamp, Mark G; Blom, Nico A; Elders, Bernadette B L J; Gittenberger-de Groot, Adriana C; Haak, Monique C; Bartelings, Margot M; Roest, Arno A W; Jongbloed, Monique R M.
Affiliation
  • Calkoen EE; Departments of Paediatric Cardiology and Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Hazekamp MG; Department of Thoracic surgery, Leiden University Medical Center, Leiden, The Netherlands.
  • Blom NA; Departments of Paediatric Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Elders BB; Departments of Paediatric Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Gittenberger-de Groot AC; Departments of Cardiology and Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Haak MC; Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.
  • Bartelings MM; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Roest AA; Departments of Paediatric Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
  • Jongbloed MR; Departments of Cardiology and Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: m.r.m.jongbloed@lumc.nl.
Int J Cardiol ; 202: 784-95, 2016 Jan 01.
Article in En | MEDLINE | ID: mdl-26476030
ABSTRACT
Atrioventricular septal defect (AVSD) covers a spectrum of heart anomalies with a common atrioventricular connection and has an incidence of 4-5.3 per 10.000 live births. About half of the AVSDs occur in patient with Down syndrome. This review provides a bench to bedside overview of AVSD. Developmental aspects, nomenclature, anatomy, and classification of AVSD are discussed. Furthermore an overview of genetic and maternal risk factors for AVSD is provided, and available literature on (fetal) diagnosis, surgical techniques and follow-up is presented. Special attention is given to differences in developmental, anatomical and prognostic factors of AVSD between non-syndromic and Down syndrome patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heart Septal Defects Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Pregnancy Language: En Journal: Int J Cardiol Year: 2016 Document type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heart Septal Defects Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Pregnancy Language: En Journal: Int J Cardiol Year: 2016 Document type: Article Affiliation country: Netherlands