Multi-scale perturbations of protein interactomes reveal their mechanisms of regulation, robustness and insights into genotype-phenotype maps.

Filteau, Marie; Vignaud, Hélène; Rochette, Samuel; Diss, Guillaume; Chrétien, Andrée-Ève; Berger, Caroline M; Landry, Christian R

Filteau, Marie; Vignaud, Hélène; Rochette, Samuel; Diss, Guillaume; Chrétien, Andrée-Ève; Berger, Caroline M; Landry, Christian R.

Brief Funct Genomics ; 15(2): 130-7, 2016 Mar.

Article in En | MEDLINE | ID: mdl-26476431

Subject(s)

Genotype; Phenotype; Protein Interaction Mapping; Alleles; Evolution, Molecular; Gene Deletion; Protein Interaction Mapping/methods; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Stress, Physiological

Key words

genetic robustness; high-throughput screening; posttranslational modification; protein interactome perturbation; proteinprotein interaction; yeast

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Protein Interaction Mapping / Genotype Language: En Journal: Brief Funct Genomics Year: 2016 Document type: Article Country of publication: United kingdom

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