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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang, Yong; Mao, Dailing; Roswit, William T; Jin, Xiaohua; Patel, Anand C; Patel, Dhara A; Agapov, Eugene; Wang, Zhepeng; Tidwell, Rose M; Atkinson, Jeffrey J; Huang, Guangming; McCarthy, Ronald; Yu, Jinsheng; Yun, Nadezhda E; Paessler, Slobodan; Lawson, T Glen; Omattage, Natalie S; Brett, Tom J; Holtzman, Michael J.
Affiliation
  • Zhang Y; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Mao D; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Roswit WT; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Jin X; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Patel AC; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Patel DA; Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Agapov E; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Wang Z; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Tidwell RM; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Atkinson JJ; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Huang G; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • McCarthy R; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Yu J; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Yun NE; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Paessler S; Galveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
  • Lawson TG; Galveston National Laboratory, University of Texas Medical Branch, Galveston, Texas, USA.
  • Omattage NS; Department of Chemistry, Bates College, Lewiston, Maine, USA.
  • Brett TJ; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Holtzman MJ; Drug Discovery Program, Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Nat Immunol ; 16(12): 1215-27, 2015 Dec.
Article in En | MEDLINE | ID: mdl-26479788
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Cysteine Endopeptidases / Histones / Poly(ADP-ribose) Polymerases / Ubiquitin-Protein Ligases Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Cysteine Endopeptidases / Histones / Poly(ADP-ribose) Polymerases / Ubiquitin-Protein Ligases Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States