Anodal sensory nerve action potentials: From physiological understanding to potential clinical applicability.
Muscle Nerve
; 53(6): 897-905, 2016 06.
Article
in En
| MEDLINE
| ID: mdl-26505150
ABSTRACT
INTRODUCTION:
Low-intensity electrical stimuli of digital nerves may generate a double peak potential (DPp), composed of a cathodal (caAP) and an anodal (anAP) potential in orthodromic recordings.METHODS:
We studied the effects on caAP and anAP of stimuli of variable intensity, duration, and frequency. We also applied a conditioning stimulus to study potential differences in recovery time.RESULTS:
The anAP was obtained in 33 of 40 healthy subjects (82.5%) and 4 of 20 patients with various types of sensory neuropathies (20%). Changes in stimulus duration and intensity had reciprocal effects on the amplitude of the anAP and the caAP. There were significant differences in recovery time between caAP and anAP after a conditioning stimulus.CONCLUSION:
The caAP and anAP are 2 interdependent waveforms generated by different effects of the same stimulus over axons at the verge of depolarization. Muscle Nerve 53 897-905, 2016.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Action Potentials
/
Peripheral Nervous System Diseases
Type of study:
Prognostic_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Muscle Nerve
Year:
2016
Document type:
Article
Affiliation country:
Portugal