Uniqueness of the macromolecular crystallographic phase problem.
Acta Crystallogr A Found Adv
; 71(Pt 6): 592-8, 2015 Nov.
Article
in En
| MEDLINE
| ID: mdl-26522408
ABSTRACT
Uniqueness of the phase problem in macromolecular crystallography, and its relationship to the case of single particle imaging, is considered. The crystallographic problem is characterized by a constraint ratio that depends only on the size and symmetry of the molecule and the unit cell. The results are used to evaluate the effect of various real-space constraints. The case of an unknown molecular envelope is considered in detail. The results indicate the quite wide circumstances under which ab initio phasing should be possible.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Proteins
/
Crystallography, X-Ray
/
Macromolecular Substances
Language:
En
Journal:
Acta Crystallogr A Found Adv
Year:
2015
Document type:
Article
Affiliation country:
New Zealand